Ophthalmic Surgery and Lasers

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Volume 27 (4) * April 1996 * Case Report (abstract)

HLA-B27–Associated Uveitis Presenting With Diffuse Vitritis

Alfredo Castillo, MD
Octavio Sayagues, MD
Carlos Grande, MD
Pedro Zarco, MD

ABSTRACT

A 26-year-old man complained of a sudden decrease in vision in the left eye. He had a past medical history of pauciarticular juvenile rheumatoid arthritis with a positive HLA-B27 haplotype and negative antinuclear antibodies and later development of ankylosing spondylitis. His ocular history was unremarkable. An ophthalmic examination revealed a predominant diffuse vitritis (3+) in the left eye. The uveitis improved after treatment with topical and systemic steroids. Following an extensive clinical and laboratory evaluation, a final diagnosis of HLA-B27–associated uveitis was made. Although uncommon, diffuse vitritis can occur in the setting of this uveitis and may be a predominant symptom. [Ophthalmic Surg Lasers 1996;27:321–323.]

AUTHORS

From the Departments of Ophthalmology (AC, OS, CG) and Rheumatology (PZ), Hospital de Móstoles, Madrid, Spain.

Accepted for publication September 4, 1995.

Dr. Grande is currently in the Department of Ophthalmology, Hospital de Getafe, Madrid, Spain.

Request reprints from Alfredo Castillo, MD, Avenida de Filipinas 50 7 B, 28003 Madrid, Spain.

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